Journal of General Virology

Fig. 2. DCs transport intestinally injected SAF to mesenteric nodes via lymph. Lymph was collected 8 to 16 h after intestinal injection of SAF and strong cytoplasmic inclusions of PrP were detected by immunocytochemistry in a small proportion of DCs (a) but not B (b) or T (c) lymphocytes in the thoracic duct pseudo-lymph of mesenteric lymphadenectomized rats. Only endogenous PrP was detected in DCs from PBS-injected control animals (d). Magnification x1000. In all panels, PrP was detected using the PrP-specific polyclonal antiserum 1B3 (Farquhar et al., 1989).

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