 
Microbiology Today February 2004
Making money out of microbiology is not new. Fermented
products such as beer and cheese have been made for thousands of years and played
an important part in early economies. In the 20th century the antibiotic era
contributed significantly to the commercial success of the pharmaceutical industry.
In more recent years the recombinant DNA revolution has opened up infinite possibilities
for exploiting the capabilities of micro-organisms. The biotechnology industry
has never been more buoyant and many research scientists are taking their discoveries
to the marketplace. This issue of Microbiology Today takes a close look at different
aspects making money out of microbes.
Making money from microbes

In an overview, David Onions of Glasgow University, who has successfully set up a biotech company in Scotland,
describes how this new culture of scientific enterprise has come about.
Money matters

Coming up with a great discovery is one thing, but financing its development is another matter. Simon Browning,
Managing Director of Connect Yorkshire, a support organization for early stage technology businesses, sheds some
light on ways to fund a new biotech venture. He supplements his description with two case studies.
Patent strategies for biotechnology companies

Another part of the commercialization minefield is protecting the invention on which the development is based.
Sandy Primrose and Richard Gillard, who are consultants in this field, explain all there is to know about patenting
innovations to keep the competitors at bay.
Materials Transfer Agreements - 'material' issues

Scientists in different research organization have traditionally shared materials and reagents, but an increasing
awareness of the legal and commercial issues involved - not least the potential value of intellectual property rights
arising from any research - has led to the proliferation of Materials Transfer Agreements to put such sharing a controlled,
contractual basis. Claudia Riordan, a former biochemist and trainee solicitor, sets out the many facets of this complex
field.
Making money from microbes - case studies

How was it for them? Two scientists who have taken the plunge and entered the world of spin-offs and start-ups recount
their experiences. Jeff Errington, Professor Microbiology at the Sir William Dunn School of Pathology in Oxford and Duncan
Maskell, Marks and Spencer Professor of Farm Animal Health, Food Science and Food Safety at the Cambridge University Centre
for Veterinary Science, spill the beans.
Getting into biobusiness

Finding help and advice to transform a great concept into a money-making reality can be daunting. SGM's Faye Jones has
explored the internet and come up with an annotated list of useful websites and resources to help the aspiring entrepreneur.
Biotechnology YES

You are never too young to aspire to be an entrepreneur. John Peberdy, former Director of Curriculum Development at the
University of Nottingham Institute for Enterprise and Innovation, describes a scheme to train young scientists in the
necessary skills. The annual competition is very popular and some of the winners have gone on to make their fortunes in
real life. What will become of the 2003 team from York University, who let us know the secrets of their winning formula?
Lactic acid bacteria - the uninvited but generally welcome
participants in malt whisky fermentation

Whisky production is an example of a large-scale biotech enterprise. It is generally believed that yeasts are the most
important microbes involved in the process, but as Fergus Priest of the International Centre for Brewing and Distilling,
Edinburgh, explains, lactic acid bacteria actually play a significant part in the production of the characteristic flavour
of the Scotch.
Comment - Are politicians listening?

As Peter Cotgreave, Director of Save British Science, describes in Comment, it has never been more vital for researchers to
explain their science to the general public and to get across the importance of their work to politicians.
Taking up this theme, new SGM President Hugh Pennington promises that the Society will play a
major role in bringing this about for microbiology, including a new scheme to train members in science communication.
In addition SchoolZone shows some practical ways in which microbiologists can promote their
science in schools.
Hot off the Press highlights some new developments in microbiological research published in the Society's journals -
Microbiology, Journal of General Virology, International Journal of Systematic and
Evolutionary Microbiology and Journal of Medical Microbiology. Topics covered include:
- Rapid identification of TB
- The importance of biofilms in plague
- Further evidence for simian origin of HIV
- The 'crypton' factor
- Is there life on Mars?
- Animal origins of human T cell leukaemia virus
- Benefits of retrovirus infection?
Other items include:
Last updated 13 February 2004
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